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In vitro Opposition binding scientific studies verified that MAM-2201 and AM-2201 possess nanomolar affinity for the two CD-1 murine and human CB1 and CB2 receptors, with desire to the CB1 receptor. In agreement With all the in vitro binding info, in vivo research confirmed that MAM-2201 induces visual, acoustic, and tactile impairments which were

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Competition binding experiments executed in CHO cell membranes transfected with human CB1 or CB2 receptors revealed affinity values during the low nanomolar array for both equally the analyzed compounds AM-2201 and MAM-2201 (Table 1). Equivalent success were being received analyzing affinity values of The 2 synthetic cannabinoids in mouse tissues s

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